college of animal science and technology-尊龙ag旗舰厅官网

　　 　　

basic information

name: shengru wu

date of birth: september 24^th, 1992

address：northwest a&f university yangling, shaanxi, china

degree: doctoral degree

citizenship: chinese

hometown: panzhihua, sichuan

email:

phone: (86) 187 0094 3648

discipline: animal nutrition and epigenetic, gut microbiota and gut health,      vaginal microbiota and reproduction, rumen health and ruminal microbiota, rumen microbiota mediated

education and academic experiences

associated professor in college of animal science and technology, northwest a&f university; 2021.08-now

focus on the roles of ruminal and intestinal microbiome in regulating gut health and carbohydrate metabolism, especially the host-microbiota interaction mechanism.

postdoctoral studies in department of microbiology, tumor, and cell biology, karolinska institute: 2019.09-2021.08

•projects title:

1.mechanism study for bacteria-bacteria and bacteria-host interaction:

2. vagina-microbiota 3d model for host-microbiota interaction study:

•advisors: prof juan du

postdoctoral studies in college of food science and engineering, northwest a&f university: 2018.11-2021.08

•project title:

1.intestinal microbiota and fecal microbiota transplantation from milk goat to mice to study microbe-diet-host interactions during the occurrence of subacute rumen acidosis (a kind of gastrointestinal inflammation in ruminants)

2.different feeding paradigms of yak calves during pre-weaning period changed rumen and intestinal development and function by altering gastrointestinal microbiota

3.roles of spermatozoal lncrnas, mirnas, and dna methylome in regulating paternal chronic folate supplementation induced transgenerational inheritance of acquired developmental and metabolic changes in chickens

•advisors: prof. junhu yao (dean of college of animal science and technology) and prof. xuebo liu (dean of college of food science and engineering)

master-doctor combined program student of animal nutrition, northwest a&f university: 2014.09 – 2018.06

• paternal chronic folate supplementation induced transgenerational inheritance of acquired developmental and metabolic changes in chickens

• roles of probiotics and prebiotics in regulating intestinal microbiota, gut health, and growth performance of broilers

•advisors: prof. junhu yao and prof. xiaojun yang

bachelor of animal science, northwest a&f university 09/2010 -- 07/2014

•thesis title: effect of in ovo feeding of folic acid on growth performance and immune function of broilers

•advisors: prof. junhu yao and prof. xiaojun yang

•won the “national scholarship of china” twice during my college life

•overall gpa: 3.44/4.00, overall average scores: 86.89/100

publication

published as the first authors

wu, s., ren, x., li, y., guo, w., lei, x., yao, j., & yang, x. (2017). effect of dietary astragalus polysaccharide supplements on testicular mirna expression profiles and enzymatic changes of breeder cocks. scientific reports, 7, 38864. doi: 10.1038/srep38864.

2. wu, s. r., guo, w., li, y. l., ren, x. c., lei, x. y., li, x. y., yao, j. h., & yang, x. j. (2017). mirna and pirna expression profiles of breeder cock testes detected by next‐generation sequencing. reproduction in domestic animals, 52, 203-213. doi: 10.1111/rda.12880.

3. wu, s., li, y., chen, s., liang, s., ren, x., guo, w., sun, q. z., & yang, x. (2017). effect of dietary astragalus polysaccharide supplements on testicular pirna expression profiles of breeding cocks. international journal of biological macromolecules, 103, 957-964. doi: 10.1016/j.ijbiomac.2017.05.122.

4. wu, s., guo, w., liang, s., lu, h., sun, w., ren, x., sun, q. z., & yang, x. (2018). systematic analysis of the regulatory roles of micrornas in postnatal maturation and metergasis of liver of breeder cocks. scientific reports, 8, 61. doi: 10.1038/s41598-017-18674-3.

5. wu, s., liu, y., zhu, l., han, d., bodinga, m. b., & yang, x. (2018). hepatic metabolomic profiling changes along with postnatal liver maturation in breeder roosters. biology open, 7, bio028944. doi:10.1242/bio.028944.

6. wu, s., guo, j., zhu, l., yang, j., chen, s., & yang, x. (2018). identification and characterisation of micrornas and piwi-interacting rnas in cockerels’ spermatozoa by solexa sequencing. british poultry science, 1, 1-10. doi: 10.1080/00071668.2018.1464123.

7. wu, s., liu, y., guo, w., cheng, x., ren, x., chen, s., li, x., duan, y., sun, q., & yang, x. (2018). identification and characterization of long noncoding rnas and mrnas expression profiles related to postnatal liver maturation of breeder roosters using ribo-zero rna sequencing. bmc genomics, 19, 498. doi: 10.1186/s12864-018-4891-7.

8. liu, y., wu, s., sun, w., chen, s., yang, x., & yang, x. (2018). variation in proteomics and metabolomics of chicken hepatocytes exposed to medium with or without folic acid. journal of cellular biochemistry, 119(7), 6113-6124. doi: 10.1002/jcb.26810.

9. li, x., wu, s., li, x., yan, t., duan, y., yang, x., duan, y., sun, q., & yang, x. (2018). simultaneous supplementation of bacillus subtilis and antibiotic growth promoters by stages improved intestinal function of pullets by altering gut microbiota. frontiers in microbiology. 9, 2328. doi: 10.3389/fmicb.2018.02328.

10. wu, s., liu, y., duan, y., wang, f., guo, f., yan, f., yang, x., & yang, x. (2018). intestinal toxicity of deoxynivalenol is limited by supplementation with lactobacillus plantarum jm113 and consequentially altered gut microbiota in broiler chickens. journal of animal science and biotechnology. 9:74. doi: 10.1186/s40104-018-0286-5.

11. wu, s., li, t., niu, h., zhu, y., liu, y., duan, y., sun, q., & yang, x. (2019). effects of glucose oxidase on growth performance, gut function, and cecal microbiota of broiler chickens. poultry science. 98, 828-841.

12. wu, s., guo, w., yan, t., zhou, j. h., li, y. l., zhu, y. f., duan, y.l., yang, x. j. (2019). spermatozoal mrnas expression implicated in embryonic development were influenced by dietary folate supplementation of breeder roosters by altering spermatozoal pirna expression profiles. theriogenology. 138, 102-110.

13. wu, s., guo, w., li, x. y., liu, y. l., li, y.l., lei, x. y., yao j. h., yang, x. j. (2019). paternal chronic folate supplementation induced the transgenerational inheritance of acquired developmental and metabolic changes in chickens. proceedings of the royal society b: biological sciences.

14. wu, s., cui, z., chen, x., wang, p, and yao, j. (2019). changed caecal microbiota and fermentation contribute to the beneficial effects of early weaning with alfalfa hay, starter feed, and milk replacer on the growth and organ development of yak calves. animals. 2019, 9, 921.

15. cui, z., wu, s., liu, s., sun, l., feng, y., cao, y., chai, s., zhang, g., yao, j. (2020). from maternal grazing to barn feeding during pre-weaning period: altered gastrointestinal microbiota contributes to change the development and function of the rumen and intestine of yak calves. frontiers in microbiology. 11, 485. doi: 10.3389/fmicb.2020.00485.

16. zheng, l., wu, s., shen, j., han, x., jin, c., chen, x., zhao, s., cao, y., yao, j. (2020). high rumen degradable starch decreased goat milk fat via trans-10, cis-12 conjugated linoleic acid-mediated downregulation of lipogenesis genes, particularly, insig1. journal of animal science and biotechnology. 11, 30. doi: 10.1186/s40104-020-00436-3.

17. cui, z., wu, s., li, j., yang, q., chai, s., wang, l., wang, x., zhang, x., liu, s., yao, j. (2020) effect of alfalfa hay and starter feeding intervention on gastrointestinal microbial community, growth and immune performance of yak calves. frontiers in microbiology. 11, 994. doi: 10.3389/fmicb.2020.00994.

18.wu, s., wang, j., zhu, l., ren, h., and yang, x. (2020). a novel apidaecin api-pr19 synergizes with the gut microbial community to maintain intestinal health and promote growth performance of broilers. journal of animal science and biotechnology. 11, 61. doi: 10.1186/s40104-020-00462-1.

19. wu, s., chen, x., li, t. ren, h., zheng, l., yang, x. (2020). changes in the gut microbiota mediate the differential regulatory effects of two glucose oxidases produced by aspergillus niger and penicillium amagasakiense on the meat quality and growth performance of broilers. journal of animal science and biotechnology 11, 73. doi.org/10.1186/s40104-020-00480-z

20. s.r. wu, x.d. chen, j.l. li, y.t. yang, z.h. cui, j.h. yao. (2021). effect of alfalfa hay and starter feed supplementation on caecal microbiota and fermentation, growth, and health of yak calves. animal, https://doi.org/10.1016/j.animal.2020.100019

21. wu s., cui z., chen x., zheng l., ren h., wang d., yao j. (2021) diet-ruminal microbiome-host crosstalk contributes to differential effects of calf starter and alfalfa hay on rumen epithelial development and pancreatic α-amylase activity in yak calves. journal of dairy science, https://doi.org/10.3168/jds.2020-18736.

22. wu, s., hammarstedt-nordenvall, l., jangard, m., cheng, l., radu, s. a., angelidou, p., zha, y., hamsten, m., engstrand, l., du j., ternhag, a. (2021). tonsillar microbiota: a cross-sectional study of patients with chronic tonsillitis or tonsillar hypertrophy. msystems, 6(2). doi: 10.1128/msystems.01302-20.

23. x, chen., x, su., j, li., y, yang., p, wang., f, yan., j, yao., # s, wu. # real-time monitoring of ruminal microbiota reveals their roles in dairy goats during subacute ruminal acidosis. npj biofilms microbiomes 7, 45 (2021). https://doi.org/10.1038/s41522-021-00215-6.

24. wu, s., li, x., chen, x., zhu, y., yao, j. (2021). optimizing the growth and immune of dairy calves by subdividing pre-weaning period and providing different milk volumes for each stage. animal nutrition https://doi.org/10.1016/j.aninu.2021.06.007.

published as the co-authors

25. huang, y. z., zhan, z. y., li, x. y., wu, s. r., sun, y. j., & xue, j., et al. (2014). snp and haplotype analysis reveal igf2 variants associated with growth traits in chinese qinchuan cattle. molecular biology reports. 41, 591-598.

26. shen, j., wu, s., guo, w., liang, s., li, x., & yang, x. (2017). epigenetic regulation of pro-inflammatory cytokine genes in lipopolysaccharide -stimulated peripheral blood mononuclear cells from broilers. immunobiology. 222, 308-315.

27. li, y., lei, x., guo, w., wu, s., duan, y., & yang, x., et al. (2018). transgenerational endotoxin tolerance-like effect caused by paternal dietary astragalus polysaccharides in broilers' jejunum. international journal of biological macromolecules. 111, 769.

28. li, y., lei, x., yin, z., guo, w., wu, s., & yang, x. (2018). transgenerational effects of paternal dietary astragalus polysaccharides on spleen immunity of broilers. international journal of biological macromolecules. 115, 90-97.

39. li, y. l., lei, x. y., lu, h., guo, w., wu, s. r., yin, z. c., sun, q. z., yang, x. j. (2018) age-related changes on cd40 promotor methylation and immune gene expressions in thymus of chicken. frontiers in immunology. 9, 2731. doi: 10.3389/fimmu.2018.02731.

30. ren, h., bai, h.x., su, x.d., pang, j., li, x.y., wu, s.r., cao, y.c., cai, c.j., yao j.h. (2020). decreased amylolytic microbes of the hindgut and increased blood glucose implied the improved starch utilization in the small intestine by using rumen-protected leucine in dairy calves. journal of dairy science. 103, 4218-4235. doi: 10.3168/jds.2019-17194.

31. ren, h., su, x.d., bai, h.x., yang, y.t., wang, h.r., dan, z., lu, j.b., wu, s.r., cai, c.j., cao, y.c., yao j.h. (2019). specific enrichment of microbes and increased ruminal propionate production: the potential mechanism underlying the high energy efficiency of holstein heifers fed steam-flaked corn. amb express. 9, doi: 10.1186/s13568-019-0937-8

32. cheng, x., yan, j.k., sun, w.q., chen, z.y., wu, s.r., ren, z.z., yang, x.j. (2020). effect of inorganic phosphate supplementation on egg production in hy-line brown layers fed 2000 ftu/kg phytase. animal. 14, 2246-2252.

33. pang, j., liu, l., liu, x., wang, y., chen, b., wu, s., yao, j., xu, x. (2020). a novel identified pseudomonas aeruginosa, which exhibited nitrate‐ and nitrite‐dependent methane oxidation abilities, could alleviate the disadvantages caused by nitrate supplementation in rumen fluid fermentation. microbial biotechnology. doi.org/10.1111/1751-7915.13726